neural stem cell
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Neural Stem Cell Death Mechanisms Induced by Amyloid Beta DND
... Fig. 3. Effects of Aβ 25-35 on intracellular protein levels of NSCs in proteomics. Proteomics showed the effects of 20 µM Aβ 25-35 on various intracellular proteins in NSCs. Representative 2D-E im- age obtained from ...
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Development of neural stem cell line using hypoxia-inducible gene expression system
... 5. Neural differentiation potency of stable NSC lines in vitro and in vivo The therapeutic potential of NSCs is mainly attributed to their ability to differentiate into all neural cell types ...
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Spinal Cord Regeneration in Rat using Neural Stem Cell Differentiated from Human Telencephalon
... of neural stem cells differentiated from a human telencephalon on the neural regeneration in the severed spinal ...and neural stem cell (1×) were transplanted after removing the ...
Isolation, Culture and Cryopreservaion of Neural Stem Cell
... 신경 줄기 세포의 재료로 매우 유용하게 이용될 수 있는 태아의 대뇌 조직을 냉동 보관 하고,이를 해동 시켰을 때,이 조직에서 유래한 세포가 신경 줄기 세포의 특성을 유지하고 있는지 확인하기 위하여,대뇌 조직을 작게 조각내어 이를 냉동 보관하였다.보관된 조직은 해동하여,세포를 추 출하고,배양 배지에서 배양 하였다.배양된 세포는 얼리지[r] ...
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A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type-Inducible Gene Overexpression
... neuronal cell type‒inducible transgene overexpression system is suitable for NSCs; furthermore, a combined treatment strategy based on a neuronal cell type‒ ...neuronal cell-type–inducible luciferase ...
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The protective effect of melatonin on neural stem cell against LPS-induced inflammation
... cited. Stem cell therapy for tissue regeneration has several limitations in the fact that transplanted cells could not survive for a long ...of neural stem cells ...
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Establishment of a Multipotent Neural Stem Cell Line from the Adult Mouse Cerebrum
... Previously, a glial precursor cell line (B2 cells) was generated from the primary cultures of oligodendrocytes/ astrocytes in an adult BALB/c mouse brain. These cells exhibited the cell-[r] ...
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Neurotoxicity Screening in a Multipotent Neural Stem Cell Line Established from the Mouse Brain
... swollen cell body with loss of neurites, and then nuclear disintegra- tion is ...the cell body and neurites, with vacuole ...upon cell surface receptors, result- ing in Ca 2 + overload, while ROS ...
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Apoptosis signal-regulating kinase 1 (ASK1) is linked to neural stem cell differentiation after ischemic brain injury
... We investigated the role of ASK1 in the survival, prolifera- tion and differentiation of central nervous system stem cells by using NSCs. Our data showed that after LPS induction, NSCs that had been treated with ...
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Neural stem cell transplantation at critical period improves learning and memory through restoring synaptic impairment in Alzheimer's disease mouse model
... that stem cell transplantation could serve as a potential therapeutic strategy to halt or ameliorate the inexorable disease ...for stem cell transplantation to have a therapeutic effect has ...
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Glioma produced periostin attracts human neural stem cells
... human neural stem cells Stem cells from various lineages have been well known for their migration tendency toward glioma and become attractive vehicles to deliver therapeutic genes to brain ...human ...
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Characterization of Neural Stem Cells Using the Nestin Enhancer
... 1. Neural stem cell culture Embryonic day ...single cell and wished again with ...5 cell/ml concentration. Primary cultured neural stem cells are incubated on 37 with 5% ...
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Amyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells
... the cell cycle progression of fetal neural stem ...that cell cycle progression of the cells is arrested at the G1 phase by depletion of APP-BP1, which results in a marked decrease in the ...
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Stem Cell Alchemy for Cell-Based Therapy
... 대로 발휘하기 어렵다. 둘째, 이와 같은 확장배양에 따른 분 화능 감소와 더불어, 각 줄기세포가 유래한 조직의 특성을 보 유하는 경향을 가짐으로써 보이는 분화능의 한계가 cell plasticity의 한계를 결정하므로, 특정 성체줄기세포를 이용 할 때 특정 계통의 세포로만 분화가 가능하거나 분화능이 제한 된다는 단점이 있다. 예를 들어, 지방유래 줄기세포(ADSCs) 는 ...
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Stem Cell Research in Otolaryngology
... 줄기세포란 자기 재생(self renewal)과 특정 세포로의 분화가 가능한 세포를 말한다. 모든 세포의 근간이 된다 는 뜻에서 간(幹)세포, 줄기세포, 만능세포, stem cell 이라고도 불린다. 줄기세포는 그들 자신이 체내의 어느 특정 위치에서도 특정 조직 또는 세포로 정확히 대체할 수 있는 독특한 특징을 지닌다. 그리고 이들은 특정세포 형태의 전구 세포를 만들 ...
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about stem cell treatment Everything
... for Stem Cell Research, National Research Institute of Health, Korea Research Institute of Bioscience and Biotechnology, Korea Institute of Drug Safety & Risk Management, and related organizations, as well ...
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Chemicals that modulate stem cell differentiation
... although cell differentiation may be the result of a complex orchestration of many signals from multiple signaling pathways, even a single chemical re- agent, a kinase inhibitor in this case, can alter the ...
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요 Ethics of Stem Cell Research
... 생명과 인간 에 대한 우리 사회의 가치관, 생명에 대한 조작 범위의 한 계, 난치병을 극복하고자 하는 인간의 소망, 의료산업의 발전에 대한 요구, 과학기술 발전에 대한 정치 경제적 요 구 등 여러 요소가 복잡하게 얽혀서 줄기세포 연구의 윤 리 문제와 연관되어 있기 때문이다. 따라서 줄기세포 연 구 윤리 문제와 연관된 가치의 담지자들[r] ...
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Characteristic analysis of mobility inducers for neural stem cells
... of neural stem cells (NSCs) led to the development of a novel strategy for delivering therapeutic genes to tumors in the ...Human neural stem cells (hNSCs) possess an inherent tumor tropism ...
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Stem cell passage affects directional migration of stem cells in electrotaxis
... Senescence associated ß-galactosidase activity was evaluated using the cellular senescence assay kit from Cell Biolabs according to the manufacturer's protocol. Passage 5, 10, and 15 TMSCs, hMSCs, ADSCs were ...
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