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Chronic hepatitis B

Current Antiviral Therapy for Chronic Hepatitis B ■ ■

Current Antiviral Therapy for Chronic Hepatitis B ■ ■

... CONCLUSIONS AND RECOMMENDATIONS Current therapy of chronic hepatitis B has limited long- term efficacy. Thus, careful consideration of severity of liver disease, likelihood of response, and potential ...

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Unresolved issues of immune tolerance in chronic hepatitis B

Unresolved issues of immune tolerance in chronic hepatitis B

... of chronic hepatitis B virus infection, immune-tolerant phase is characterized by high viral replication, the presence of HBV e antigen (HBeAg), and normal or minimally elevated serum alanine ...

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Characterization of antiphospholipid antibodies in chronic hepatitis B infection

Characterization of antiphospholipid antibodies in chronic hepatitis B infection

... In most cases, infection-associated aPLs appear tempora- rily and disappear within 2 or 3 months [24, 25], and except in rare cases, they are unrelated to thrombotic complications. Contrary to previous reports, in the ...

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Oral antiviral agents for treatment of chronic hepatitis B

Oral antiviral agents for treatment of chronic hepatitis B

... for chronic hepatitis B virus (HBV) infection is to eliminate or suppress HBV with the aim of preventing the devastating complications of cirrhosis, hepatic failure, and hepatocellular ...for ...

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Natural History and Treatment Indications of Chronic Hepatitis B

Natural History and Treatment Indications of Chronic Hepatitis B

... 면역활동기(HBeAg-positive chronic hepatitis B, immune active phase or immune active HBeAg-positive chronic hepatitis B) 바이러스에 대한 면역 반응이 시작되는 ...

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Hepatitis B Viral Surface Mutations in Patients with Adefovir Resistant Chronic Hepatitis B with A181T/V Polymerase Mutations

Hepatitis B Viral Surface Mutations in Patients with Adefovir Resistant Chronic Hepatitis B with A181T/V Polymerase Mutations

... Hepatitis B Viral Surface Mutations in Patients with Adefovir Resistant Chronic Hepatitis B with A181T/V Polymerase Mutations The hepatitis B virus (HBV) polymerase gene ...

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만성 B형간염의 개별화 치료 =Individualized therapy for chronic hepatitis B

만성 B형간염의 개별화 치료 =Individualized therapy for chronic hepatitis B

... Yuen MF , Hui CK , Cheng CC , Wu CH , Lai YF , Lai CL Long-term fol1ow-up of interferon alfa treatment in Chinese patients with chronic hepatitis B infection 매 e effect on hepatitis B e [r] ...

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Analysis of Drug Utilization in Patients with Chronic Hepatitis B

Analysis of Drug Utilization in Patients with Chronic Hepatitis B

... with chronic hepatitis B infection is to prevent progression of the disease to cirrhosis and hepatocellular ...of chronic hepatitis B (CHB) medications in South Korea between ...

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Clevudine Is Highly Efficacious in Hepatitis B e
Antigen-Negative Chronic Hepatitis B with Durable
Off-Therapy Viral Suppression

Clevudine Is Highly Efficacious in Hepatitis B e Antigen-Negative Chronic Hepatitis B with Durable Off-Therapy Viral Suppression

... The endpoint of treatment for HBeAg-negative chronic hepatitis B is not established. HBeAg loss or se- roconversion cannot be used to define response and treat- ment usually focuses on suppression of ...

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Elecsys Hepatitis B Surface Antigen Quantitative Assay: Performance Evaluation and Correlation with Hepatitis B Virus DNA during 96 Weeks of Follow-up in Chronic Hepatitis B Patients

Elecsys Hepatitis B Surface Antigen Quantitative Assay: Performance Evaluation and Correlation with Hepatitis B Virus DNA during 96 Weeks of Follow-up in Chronic Hepatitis B Patients

... with chronic hepatitis ...Serum hepatitis B surface antigen quantitation can reflect hepatitis B virus in the liver and predict treatment ...

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Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study

Management of Clevudine-Resistant Chronic Hepatitis B: A Multicenter Cohort Study

... Various rescue therapies have been used for CLV-resistant This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ...

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Prediction models of hepatocellular carcinoma development in chronic hepatitis B patients

Prediction models of hepatocellular carcinoma development in chronic hepatitis B patients

... INTRODUCTION Chronic hepatitis B virus (HBV) infection is the main cause of cirrhosis, hepatic failure, and hepatocellular carcinoma (HCC) globally [1] ...Of chronic HBV carriers, ...

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Hepatic Sarcoidosis in a Patient with Chronic Hepatitis B Virus Infection

Hepatic Sarcoidosis in a Patient with Chronic Hepatitis B Virus Infection

... with chronic hepatitis B infection and lab findings were within normal range, the CT scan showed hepatosplenomegaly and multiple lymph node ...vealed chronic granulomatous inflammation showing ...

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Factors Influencing Self-Management Compliance of Patients with Chronic Hepatitis B

Factors Influencing Self-Management Compliance of Patients with Chronic Hepatitis B

... Eum, S. Effect of the structured education for knowledge of hepatitis B type and self- care behavior in chronic hepatitis B patients. Chronic disease self-management and adherence to [r] ...

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Pattern of Mutations in Hepatitis B Virus Reverse Transcriptase Gene during Lamivudine Therapy in Patients with Chronic Hepatitis B Virus Infection

Pattern of Mutations in Hepatitis B Virus Reverse Transcriptase Gene during Lamivudine Therapy in Patients with Chronic Hepatitis B Virus Infection

... We investigated the pattern of mutations in and outside of YMDD motif of HBV reverse transcriptase gene during lamivudine therapy in patients with chronic hepatitis B infection.. Methods[r] ...

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Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies

Management of entecavir-resistant chronic hepatitis B with adefovir-based combination therapies

... Tenofovir may be the best option, but it is still not available in many countries. Where tenofovir is not available, adefovir plus entecavir can be considered an alternative treatment option in patients with favorable ...

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Clinical Significance of Hepatitis B Surface Antigen Quantification in Chronic Hepatitis B

Clinical Significance of Hepatitis B Surface Antigen Quantification in Chronic Hepatitis B

... 만성 B형간염의 자연경과는 1) immune tolerance phase, 2) immune clearance phase, 3) immune control/inactive phase, 4) reactivation/HBeAg negative hepatitis와 같이 크게 4개의 phase로 나눌 수 있다. 모든 환자가 4개의 phase 를 순차적으로 경험하는 것은 아니며 phase 간 이동이 ...

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Antiviral Therapy for Chronic Hepatitis B

Antiviral Therapy for Chronic Hepatitis B

... hronic hepatitis B infection is the most common cause of chronic liver diseases in Korea and can induce chronic hepatitis, liver cirrhosis, and hepatocellular ...

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Anti - -viral Treatment of Chronic Hepatitis B

Anti - -viral Treatment of Chronic Hepatitis B

... HBV의 증식 상태가 소멸되는 것이 꼭 조직 소견의 호전과 비례하지 않는 경우도 있지만 만성 B형 간염 환자에서 HBeAg이 빨리 없어지는 것이 좋다.. HBeAg 양성인 만성 B형 간염 환자 중 매년 5~15%에 서 HBeAg이 자연 소실된다.[r] ...

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New Potential Therapies for Chronic Hepatitis B

New Potential Therapies for Chronic Hepatitis B

... 1) 직접 작용 항바이러스제 (1) HBV entry inhibitors 최근 HBV가 숙주세포 내로의 진입에 중요한 역할을 하는 NTCP 수용체가 발견되면서 진입 억제제(entry inhibitor)의 개발이 시작되었다. 가장 대표적인 myrcludex B는 NTCP 수 용체에 HBV와 경쟁적으로 결합하여, HBV의 결합과 침입을 막는 합성 지방펩티드(lipopeptide)이다. 간세포 ...

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