blood brain barrier
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Blood-brain barrier disruption after cardiac surgery
... the blood brain barrier, which has been described in patients with transient symptoms without DWI ...the blood brain barrier, a process also seen in patients with traumatic ...
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AKAP12 Supports Blood-Brain Barrier Integrity against Ischemic Stroke
... * Correspondence: lo@helix.mgh.harvard.edu (E.H.L.); karai@partners.org (K.A.); Tel.: +1-617-726-4043 (E.H.L.); +1-617-724-9503 (K.A.) Received: 28 October 2020; Accepted: 22 November 2020; Published: 28 November 2020 ...
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Blood Brain Barrier and Brain Tissue Injury by Gd-DTPA in Uremia-induced Rabbits
... Conclusion: Injuries to the blood brain barrier and neighbouring brain tissue were aggravated by Gd-DTPA administration in uremia-induced rabbits. These findings appear[r] ...
Strategy for Maintenance of Blood Brain Barrier Integrity and Neuroprotection in Experimental Stroke
... 아그마틴의 혈관장벽 안정화에 미치는 효과(Effect of agmatine on the blood-brain barrier integrity) 아그마틴과 알기닌은 흰쥐, 토끼에서 체순환에서 혈압을 감 소시키는 역할을 하며, 이것은 NOS 억제제인 L-NAME에 민감하게 억제된다. 38 아그마틴은 분리된 심장에서 허혈-재관 류 손상으로부터 심장을 보호하는 ...
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Blood-brain barrier disruption in humans is independently associated with increased matrix metalloproteinase-9
... and blood brain barrier ...in blood brain barrier disruption or is a marker of the severity of the ongoing damage to the blood brain barrier following ...
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Assessment of Blood-Brain Barrier Permeability by Dynamic Contrast-Enhanced MRI in Transient Middle Cerebral Artery Occlusion Model after Localized Brain Cooling in Rats
... Corwin F, et al. The permissive nature of blood brain barrier (BBB) opening in edema formation following traumatic brain injury. Acta Neurochir Suppl 2000;76:125-129 45. Bisdas S, Naegele T, ...
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Blood-brain barrier stabilization effects of agmatine assessed by dynamic contrast-enhanced MRI in a rat model of transient cerebral ischemia
... Data are presented as mean ± standard deviation. ADC: apparent diffusion coefficient, FA: fractional anisotropy, BBB: blood-brain barrier. DCE-MRI showed increase in permeability parameters in the ...
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The Blood-Brain Barrier Permeability and Pharmacokinetics of Nitrone Based Spin Trapping Agent, α-Phenyl-n-tert-Butyl Nitrone (PBN) in Rats
... The brain uptake of PBN after IV injection at 120 min was ...the brain through the BBB well in rats, because PBN is small molecule (MW 177) and lipid-soluble (log P ...(PBN), blood-brain ...
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Introduction Effect of Hypothermia on the Blood Brain Barrier Integrity after Focal Cerebral Ischemia
... The C-terminal cytoplasmic domain of occludin binds to the GuK region of ZO-1 in vitro, and this interaction may serve to link occludin to the actin cytoskeleton. 35,36 Similarly, ZO-2 and ZO-3 bind to the C-terminus of ...
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Effects of Salviae Miltiorrhizae Radix on Blood-Brain Barrier Impairment of ICH-Induced Rats
... Objectives : This study was performed in order to evaluate the effects of Salviae Miltiorrhizae Radix (SMR) water extract against the cerebral hemorrhage and the [r] ...
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The Effects of Onion and Yuzu Extracts against Ischemia/Hypoxia-Induced Dysfunction of Blood-Brain Barrier
... 아주대학교 대학원 의생명과학과 현 수 왕 (지도 교수: 이 수 환/정 이 숙) 뇌졸중 또는 중풍이라고 불리는 뇌혈관질환은 암, 심장질환과 함께 우리나라 3대 사망원인 질환의 하나로써 매년 그 수가 늘어나고 있다. 특히, 뇌혈관이 터 지는 뇌출혈에 비해 동맥경화, 고지혈증 등으로 혈관이 막혀 발생하는 서구형 질 환인 뇌경색 환자가 급증하고 있으며, 뇌경색으로 인한 뇌졸중의 비율이 전체 뇌 ...
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The Effect of Micro-Particles of Linoleic Acid Emulsion on the Blood-Brain Barrier in Cats
... 결론적으로, 리놀레산 유상액을 뇌 내경동맥에 주입한 후 관 찰한 자기공명영상 소견에서 리놀레산 유상액은 혈뇌장벽을 손 상시켜 투과성 증가를 보였으며 1일 영상에서는 혈뇌장벽의 투 과성은 정상으로 돌아왔음을 알 수 있었다.. 이런 결과는 지방이 혈뇌장 벽에 미치는 영향에 대한 기전을 이해하는 데 도움을 주며 인 위적으로 혈뇌장벽을 열[r] ...
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Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption?
... chemiluminescence system. The bands were visualized with an enhanced chemiluminescence reagent (ECL plus Western blot analysis system; Amersham Biosciences, Piscataway, NJ). Detection of oxidative stress by in situ HEt ...
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Plastic roles of pericytes in the blood-retinal barrier
... he blood–retinal barrier (BRB) is divided into inner and outer parts 1,2 ...the blood–brain barrier (BBB) and BRB 5–7 ...and brain vessels through controlled platelet-derived ...
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Characterization of the Brain Transport and Brain-to-Blood Efflux of Nitrone Based Antioxidant, PBN
... 높은 뇌 이행량을 나타내는 것을 알 수 있었다 .^ 이와 같이 PBN 은 뇌로 잘 이행되는 것이 알려져 있지만，그 수송 특성에 대해서는 이제까지 보고된 바가 없다 . Choline(Fig. 1) 은 세포막의 구성성분이고 신경전달물질인 acetylcholine 의 전 구물질로써 유기양이온 (organic cation) 성 약물이다 . 혈액•뇌 관 문 ...
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Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors
... and brain can be mediated by several direct and indirect ...the blood circulation to interact with the host immune system and metabolism that directly signals the ...epithelial barrier integrity, ...
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Experimental Model for Research on the Blood-Ocular Barrier
... *: Mean delayed contrast enhancement ratios (= [signal intensity of postcontrast image of 3 hours - signal intensity of precontrast image of 30 minutes]/signal intensity of precontrast i[r] ...
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Temporary Opening of the Testis-blood Barrier by Triolein Fat Emulsion
... 그리고 Kim 등 12 은 고양이 모델에서 가돌리니움 조영제를 사용한 자기 공명영상 검사를 통하여 트리올레인 유상액이 혈뇌장벽의 투과성 변화를 야기한다고 하였다.. 저자들도 혈고환장벽의 투과성 변화를 알아보기 위하여 가돌리니움 조영제를 사용 한 자기공명영상 검사를 시행하였다.[r] ...
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Current State and Prospects of Development of Blood-based Biomarkers for Mild Traumatic Brain Injury
... trauma. Blood-based biomarkers are expected to play an important role in diagnosing mTBI and predicting functional outcomes, due to their feasibility and the recent progress of targeted proteomics techniques ...
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Epidermal Permeability Barrier Defects and Barrier Repair Therapy in Atopic Dermatitis
... permeability barrier function and the systemic immune reaction in ad: thymic stromal lymphopoietin (TSLP) TSLP is an interleukin-7-like cytokine produced by epithelial cells that triggers dendritic cells to induce ...
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