angiotensin-II receptor blocker
Combination of a peroxisome proliferatoractivated receptor-gamma agonist and an angiotensin II receptor blocker attenuates myocardial fibrosis and dysfunction in type 2 diabetic rats
... an angiotensin II receptor blocker (ARB), a peroxisome proliferator-activated receptor (PPAR)-gamma agonist, and their combination on myocardial fibrosis and function in type 2 diabetic ...
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Severe Hyponatremia Associated with the Use of Angiotensin II Receptor Blocker/thiazide Combinations
... of angiotensin II receptor blo- cker (ARB)/ ...of angiotensin II, hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption and increases excretion of sodium ...
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Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease on Effect of Reducing Proteinuria
... 는 angiotensin I 을 축적시키고 이는 angiotensin II 수용체를 자극한다 이렇게 자극 ...된 angiotensin II 수용체는 혈관수축 염 저류 염증 섬유화와 교감신경계를 흥분시 , , , 키는 나쁜 영향을 조장한다 (Goodfriend , ...면 angiotensin II 의 ...
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Comparison of effects between calcium channel blocker and diuretics in combination with angiotensin II receptor blocker on 24-h central blood pressure and vascular hemodynamic parameters in hypertensive patients: study design for a multicenter, double-blinded, active-controlled, phase 4, randomized trial
... However, a well-known side effect of CCBs are periph- eral edema and vasoconstriction. ARBs can reduce these side effects by antisympathetic effects and venous dila- tion. In addition, ARBs can lower the effect of ...
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Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway
... Ang II-dependent vascular aging mechanism and anti-senescent effect of ...Ang II-induced senescence in ...Ang II-induced cellular senescence ...Ang II-induced animal aging ...
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Role of Angiotensin Receptor Blocker for Treatment of Cardiovascular Diseases: Beyond BP Lowering
... 추계학술대회 Angiotensin II는 angiotensin I으로부터 angiotensin converting enzyme에 의해 생성되는 물질로 혈관의 병 태 생리에 가장 중요한 역할을 하는 ...물질이다. Angiotensin II는 혈관을 수축시키고 비후시키며 혈관내 염증매개 물질을 활성화시키고 또한 혈전 형성에 관여하는 PAI-1을 ...
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Angiotensin II potentiates zinc-induced cortical neuronal death by acting on angiotensin II type 2 receptor
... μM angiotensin II, angiotensin II alone, zinc plus 1 μM PD123319, or PD123319 ...Whereas angiotensin II or PD123319 alone had no effect on the level or distribution of p67 phox , ...
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Angiotensin II type 1 receptor antibodies in kidney transplantation
... Korea Angiotensin II type 1 receptor (AT1R) antibodies directly injure endothelial and vascular smooth muscle cells by activating tran- scription factors associated with proinflammatory ...
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Impact of Angiotensin Converting Enzyme Inhibitor versus Angiotensin Receptor Blocker on Incidence of New-Onset Diabetes Mellitus in Asians
... of angiotensin I to angiotensin II, but also by inhibiting the degradation of ...giotensin II inhibition by interacting selectively with the receptor site, and thus, may result in ...
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PPAR Agonist and Angiotensin II Receptor Antagonist AmeliorateRenal Tubulointerstitial Fibrosis g
... After TGF- b binds to the TGF- b receptor II, phosphoryla- tion of the TGF- b receptor I, and the intracellular substrates, Smad2 and Smad3, occurs. When activated, these Smads with their common ...
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Synergistic protective effects of a statin and an angiotensin receptor blocker for initiation and progression of atherosclerosis
... ARB, angiotensin II receptor blocker; Arg-1, arginase-1; combi, combination of statin and ARB; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; IL-1β, interleukin 1 beta; IL-6, interleukin 6; ...
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Cardioprotective Effect of Fimasartan, a New Angiotensin Receptor Blocker, in a Porcine Model of Acute Myocardial Infarction
... effect of blocking the renin-angiotensin-aldosterone system may take a longer period to be significant as shown in The On- going Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (ONTARGET) ...
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The impact of a dose of the angiotensin receptor blocker valsartan on post-myocardial infarction ventricular remodelling
... the angiotensin II concentration in patients who receive ACE inhibitor treat- ...vigorous angiotensin suppression might be deleterious in the presence of background beta- blocker ...
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Angiotensin II AT
... Ang II AT1 receptor blocker candesartan treatment in rats with CRF, where plasma vasopressin and AngII levels are elevated, could alter the downregulation of renal AQP2 expression and dec- reased ...
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Effect of Statins, Metformin, Angiotensin-Converting Enzyme Inhibitors, and Angiotensin II Receptor Blockers on Age-Related Macular Degeneration
... Using a cohort of elderly patients from the Korean National Health Insurance Service database, this nested case-control study aimed to determine whether users of statins, metformin, A[r] ...
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Clinic and Home Blood Pressure Lowering Effect of an Angiotensin Receptor Blocker, Fimasartan, in Postmenopausal Women with Hypertension.
... ACEIs or ARBs may be an appropriate option in this situation. In post-MPW with hypertension, an ACEI lowered diastolic BP effectively with the same amount that a diuretic did, but a diuretic had more metabolic ...
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The Effect of an Angiotensin Receptor Blocker on Arterial Stiffness in Type 2 Diabetes Mellitus Patients with Hypertension
... A previous study analyzing the effects of T2DM with hyper- tension on the arterial wall has reported a highly significant correlation between PWV and the fasting glucose level, among the various risk factors [26]. The ...
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새로운 고혈압 치료제 : All Receptor Blocker
... Kurland L, Melhus H, Karlsson J, Kahan T , Malmqvist κ Ohman P, Nystrom F , Hagg ALind L: Polymorphisms in the angiotensinogen and angiotensin II ψpe 1 receptor gene are relat[r] ...
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Combined vascular effects of HMG-CoA reductase inhibitor and angiotensin receptor blocker in non-diabetic patients undergoing peritoneal dialysis
... 6 Severance Biomedical Science Institute, Brain Korea 21, Yonsei University, Seoul, Korea *Correspondence and offprint requests to: Shin-Wook Kang; E-mail: kswkidney@yuhs.ac Abstract Background. Statins and ...
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An Angiotensin Receptor Blocker Prevents Arrhythmogenic Left Atrial Remodeling in a Rat Post Myocardial Infarction Induced Heart Failure Model
... The limitation of this study is that we did not measure the di- rect angiotensin II level in the atrial tissue. However, the incre- ase in the angiotensin II levels has already been ...
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