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RNA Interference

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Academic year: 2021

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Table  1.  The  sequences  of  siRNA  used  in  the  experiment siRNA Sequence TNFRI-seq1 5'-GGAGCTTACTTGTATGATGAT  -3'   (sense),  5'-GGAACCTACTTGTACAATGAC  -3'   (anti-sense) TNFRI-seq2 5'-ACTATCTCAGATACTGTCTTA  -3'   (sense) 5'-ACCACCTCAGACACTGCCTCA  -3
Fig.  1.  Inhibition  of  TNFRI  mRNA  by  TNFRI  specific  siRNA  in  articular  chondrocytes
Fig.  3.  Inhibition  of  TNFRI  mRNA  and  protein  by  TNFRI  specific  siRNA  in  RA  fibroblast  like  synoviocytes(FLS)
Fig.  4.  Inhibition  of  MMP-1  secretion  induced  with  TNF- TNF-α  by  TNFRI  siRNA

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