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High glucose and palmitate increases bone morphogenic protein 4 expression in human endothelial cells

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Fig. 1. Glucose increased expression of BMP4 in dose-dependent  manners. After 16~24 h plating, the cells were washed with DMEM  media (containing 2% FBS, w/o growth factor), and then incubated with  glucose (D-glucose 100, 500, 1000 mg/dL), and mannitol (
Fig. 2. High glucose and FFA increased expression of BMP4 in time- time-dependent manners
Fig. 4. High glucose and FFA induced BMP4 activation increase  monocyte adhesion. We used siRNA techniques to selectively deplete  BMP4-dependent pathways and examine the effect of HG, PAL, HG/PAL  with DMEM media (containing 2% FBS, w/o growth factor) for

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