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류마티스관절염 활막세포에서 TLR3 자극에 따른 MIF 생성의 증가

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Academic year: 2021

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Fig. 1. Increased  expression  of  MIF,  IL-6,  TNFα and  IL-1β in  RA  synovium.  Immunostaining  was  performed  using  the  specific  antibodies  against  MIF,  IL-6,  TNFα and  IL-1β in  synovial  biopsy  samples  from  patients  with  rheumatoid  arth
Fig. 3. Enhancement  of  MIF  production  by  the  stimulation  of  TLR3  or  TLR4  engagement  in  FLS  from  patients  with  RA
Fig. 5. Blockade  of  the  IL-6-induced  decrease  in  MIF  by  the  engagement  of  TLR3  and  TLR4  in  RA  FLS
Fig. 6. Increased  level  of  MIF  and  IL-6  in  the  synovial  fluid  and  sera  derived  from  patients  with  RA,  OA  and  HC

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