Surgical Treatment of Hepatic Metastasis of Renal Epithelioid Angiomyolipoma with Multiple Metastases
Dongho Choi, M.D., Kyeong Geun Lee, M.D., Han Joon Kim,
M.D., Hwon Kyum Park, M.D., Oh Jung Kwon, M.D. and
Kwang Soo Lee, M.D.
Department of Surgery, College of Medicine, Hanyang University,
Seoul, Korea
Angiomyolipoma is a benign renal tumor composed of thick- walled blood vessels, smooth muscle cells, and adipose tissue. Despite the aggressive biological and histological features associated with angiomyolipoma, the lack of distant metastasis led us to conclude that angiomyolipoma is a benign neoplasm. Epithelioid angiomyolipoma is a recently
described variant type of angiomyolipoma of the kidney.
Diagnosis is usually made by histological method and im- munohistochemical staining with HMB-45. Several reports suggested the presence of malignant epithelioid angiomyo- lipomas showing multiple metastases and local aggres- siveness. We report a case of epithelioid angiomyolipoma with multiple metastases. Local recurrence and liver, bone and lung metastases developed 11 months after radical nephrectomy. Right hepatectomy and wedge resection of left lobe of the liver with radiation therapy were done.
(Korean J HBP Surg 2002;6:103-106)
Key Words: Epithelioid angiomyolipoma, Nephrectomy, Liver metastasis
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