this study is to evaluate the role of combined therapeutic modalities and surgical resection in hepatoblastoma

(1)

The Results of Combined Therapeutic Modalities for Hepatoblastoma

Airi Han, Jung-Tak Oh, Seok Joo Han, Seung Hoon Choi and Eui Ho Hwang

Department of Pediatric Surgery, Yonsei University College of Medicine Seoul, Korea

In hepatoblastoma,

encouraging

cure rates have been achieved with recent advances in chemotherapy and surgical techniques, The aim

of

this study is to evaluate the role of combined therapeutic modalities and surgical resection in hepatoblastoma

.

Fifteen cases of hepatoblastoma were treated from January 1993 to August 2000. Six patients had resectable tumors at initial diagnosis. All underwent

surgical

resection

and

in four patients postoperative adjuvant

chemotherapy

was needed. Nine out of 15 patients had unresectbale tumors

at

initial diagnosis

, and

preoperative

chemotherapy

was applied. There was one operative mortality and 14 patients

showed

good prognosis after

surgery.

Although various treatment modalities

should

be combined for the unresectable hepatoblastoma. surgical resection remains the major

curative

procedure

. (J Kor Assoc Pediatr Surg 7(1):37-41. 2(01)

Index Words: Hepatoblastoma. SurJriml resection. Preoperative chemotherapy

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Correspondence :

Eui /fo HW4ng, MD., Department of Pediatri~

Surgery, Yonsei University College of Medicine.

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Trisegmentectomy (1) Wedge resection(1)

Fig 1. Clinical course of 15 patients with hepatoblastoma. The 5 year survival measured by Kaplan-Meier methods is 92

% (* : Surgical mortality by hepatic failure. Ten courses of preoperative chemotherapy followed by left. trisegmentectomy).

(3)

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