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The Effect of Antidepressants on Mesenchymal Stem Cell Differentiation

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Fig. 1. Effect of antidepressants on mineralization. Human mesenchymal stem cells (MSCs) were induced to differentiate into osteoblasts for 3  weeks at 37°C in the presence of various concentrations of (A, B) amitriptyline, (C, D) venlafaxine, or (E, F) fl
Fig. 3. Effect of antidepressants on adipogenesis. Human mesenchymal stem cells were induced to differentiate into adipocytes for 2 weeks at  37°C in the presence of various concentrations of (A, B) amitriptyline, (C, D) venlafaxine, or (E, F) fluoxetine
Fig. 4. Assessment of cell viability. Human mesenchymal stem cells (MSC) induced to differentiate into osteoblasts (alizarin red [AR]) or adipo- adipo-cytes (oil red O [ORO]) in the presence of various concentrations of amitriptyline (Ami), venlafaxine (Ve

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