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Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors

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Figure 1. Dynamic homeostasis of the gut epithelium and gut barrier integrity. (A) Gross features of the small intestine
Figure 2. The dynamic communication of the gut microbiota-brain axis. Bidirectional communication between the gut and brain can be mediated by several direct  and indirect pathways
Figure 3. Gut-brain system crosstalk via immunity and HPA axis after stroke. Stroke induces dysbiosis, mucosal barrier dysfunction, an increase in gut  permeability, and bacteria translocation, leading to post-stroke infection
Figure 4. The role of AhR signals in the gut and brain. (A) Upon agonist binding, AhR and some components of the chaperone complex translocate to the  nucleus, where AhR binds DNA-responsive elements to control target gene expression such as the CYP1A1
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