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￭ S-243 ￭
Association of anemia with the risk of sudden cardiac arrest in general population
1Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea
*In-Jung Kim1, Pil-Sung Yang1, Tae-Hoon Kim1, Jae-Sun Uhm1, Hui-Nam Pak1, Moon-Hyoung Lee1, Boyoung Joung1
Introduction: Anemia might be associated with an increased sudden cardiac arrest (SCA) in cardiovascular disease. However, the relationship between anemia and SCA is still unclear in general population. Methods: In Korean National Health insurance Service-National Sample Cohort, 499,103 sub- jects who received national health check-up after 2009 were enrolled, and follow up until 2013. We defined anemia according to WHO criteria. Results: Of the 499,103 subjects, 11.98% were anemic. During the mean follow-up period of 45.5±14.9 months, 0.5% of anemic patients died compared with 0.15% of nonanemic patients. Crude mortality risk of anemia was hazards ratio (HR) 3.24 (95% confidence interval (CI) 2.83 to 3.71, p
＜0.001). Lower baseline hemoglobin values were associated with increased crude mortality rates (r＝-0.396, p＝0.025). Adjusted HRs showed an in- creased risk for anemia (HR 1.99[95% CI : 1.73 to 2.30, p＜0.001]). Especially, anemia increased risk of sudden cardiac arrest in young age (HR 2.83[95% CI : 2.23 to 3.6, p＜0.001]) and subgroup without comorbidities (HR 2.09 [95% CI : 1.65 to 2.64, p＜0.001 in no hypertension], HR 2.01[95% CI : 1.66 to 2.44, p＜0.001 in no diabetes mellitus]). Conclusions: Anemia was associated with increased risk of SCA in general population.
Lower baseline hemoglobin values were associated with increased crude mortality rates. Anemia should be considered as a useful prognosticator, and therapeutic strategies aimed to increase hemoglobin levels in general population should be investigated.
￭ S-244 ￭
Occlusive Vasospasm in Patient with Corrected Transposition of the Great Arteries
1 여수전남병원, 2 전남대학교병원
*이림1, 정명호2, 김지은2, 김민철2, 심두선2, 홍영준2, 김주한2, 안영근2
Coronary artery anomalies may be associated with congenital heart diseases such as Transposition of the Great Arteries (TGA), the presence of a single ventricle and Tetralogy of Fallot. The incidence of coronary artery disease in congenital heart disease was very low. In addition, there are limited reports about coronary vasospasm in patients with TGA. We report a case which described anomalous origin of the coronary artery with congenital heart dis- ease that was coexistent with variant angina. A 64-year-old woman who has underlying disease of corrected TGA, atrial fibrillation and cerebral in- farction complained chest pain which radiating left shoulder. Coronary angiography revealed no fixed stenosis expect for coronary artery anomaly which showed same origin of right coronary artery (RCA) and left circumflex artery (LCX), and single origin of left anterior descending artery (LAD) (Figure: same origin of RCA and LCX (top panels, open arrow) and single origin of LAD (top panels, arrow head). However, ergonovine challenge test provoked total occlusive spasm in mid RCA which was completely relieved by intracoronary nitroglycerine (Figure: bottom panels). To the best our knowledge, this case is first case of variant angina pectoris coexisting with corrected TGA.
