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Immunomodulatory effect of the water extract of Aster tataricus through mitogen-activated protein kinase signaling pathway

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Fig. 1. The effect of AT extract on cell-viability and proliferation of THP-1 cells. THP-1 cells (5 × 10 4 /well) were  cultured with ethanol extract or water extract of AT (50 μg/mL), respectively, for 24 hours (A) or 72 hours (B)
Fig. 2. The water extract of AT induces cytokine secretion by THP-1 cells. (A) THP-1 cells were cultured with ethanol extract or water extract of AT (50 μg/mL)  for 48 hours, and then further incubated in the presence or absence of LPS (10 ng/mL) for 24 ho
Fig. 3. The AT water extract increases the protein expression levels of COX-2 and iNOS in THP-1 cells
Fig. 4. The AT water extract induces the phosphorylation of MAPK and Akt and the degradation of IκBα in THP-1 cells
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