that complete surgical resection of hepatoblastoma

(1)

64

5:o}~ 3!} : All 7.:r:l All 1 ~ 2001 \:! ^Vo^l.^{7, No.} 1. June 2001

~A-11~7t~~~~ ~-"2-A-11x%~lAl .;;-~ BJAt~~lliS4- 78~%~ ~~R~ 4- ~A-117t 7t~~~~ 1011 ~jl

A Case of Successful Hepatic Resection after Local Radiotherapy with Combined Transarterial Chemoinfusion in Hepatoblastoma

Airi Han, M.D., Jung-Tak Oh, M.D., Seok Joo Han, M.D., Seung Hoon Choi, M.D., Eui Ho Hwang, M.D.

Department of Pediatric Surgery, Yonsei University College of Medicine Seoul, Korea

It

has been widely

accepted

that complete surgical resection of hepatoblastoma

is

essential for

long-term

survival. But unfortunately less than 50

%

of hepatic tumors in children can be totally removed at the time of diagnosis

.

This report is to present the experience of successful resection of hepatoblastoma

after concurrent

radiotherapy with transarterial chemoinfusion in a

child.

We believe this modality of treatment

enables

complete resection of

unresectable

hepatoblastoma. which is

resistant

to the systemic chemotherapy.

(J Kor Assoc Pediatr Surg 7(1):64- 67. 2(01)

Index Words: Hepatoblastoma, Radiotherapy. Transarterial chemoinfusion, Complete resection

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Fig. 1. Abdominal computed tomogram. A large mass occupied right lobe and left medial lobe of the liver.

Fig. 2. Microscopic finding of the tumor showing irre- gular plates of large polygonal cells with round to oval nuclei and granular cytoplasm (arrow), which is consi- stent with hepatoblastoma, fetal type (H&E, x 100).

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Fig. 3. Hepatic arteriography. Right hepatic artery supplies a hypervascular tumor.

Fig. 4. Abdominal computed tomogram showing marked reduced tumor size and enlarged left lateral lobe.

Fig. 5. Microscopic finding of the resected mass with few viable tumor cells (arrow). The tumor showed the changes from previous choemradiotherapy, enlarement of nuclei and vacuolation of cytoplasm, disterted sinusoidal plates (H&E, x 400).

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(4)

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