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Transplantation of Neural Differentiated Human Mesenchymal Stem Cells into the Cochlea of an Auditory-neuropathy Guinea Pig Model

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Academic year: 2021

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Fig. 1. Photomicrographs of stem cell transplantation method. (A) Visualization of the round window after opening the bulla
Fig. 2. Ouabain-induced spiral ganglion neuropathy. (A) There is a severe loss of spiral ganglion neurons (SGNs) without a loss of hair cells after 7 days of ouabain application (H
Fig. 4. Confocal microscope image after immu-  nostaining for anti-human nuclei and NF-H
Fig. 6. Auditory brainstem response (ABR) results after  nhMSC transplan tation. Click-evoked ABR waves are  recorded up to -10 ± 10 dB in normal guinea pigs

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