A Clinical Pilot Study Comparing Sweet Bee Venom parallel treatment with only Acupuncture Treatment in patient diagnosed with lumbar spine sprain

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요추부 염좌로 진단받은 환자에 대한

Sweet Bee Venom 병행 치료와 단독 침 치료의 효과 비교

A Clinical Pilot Study Comparing Sweet Bee Venom parallel treat- ment with only Acupuncture Treatment in patient diagnosed with

lumbar spine sprain

Original Article

Shin Yong-jeen

Suncheon Oriental Medical Hospital, Wonkwang University.

Corresponding author : Shin Yong-Jin. #544, Jorye-dong, Suncheon-si, Jeonnam

Tel:(061)720-7521, Fax:(061)720-7550, E-mail:[email protected] Key Words:

Lumbar spine sprain, Sweet Bee venom, Acupuncture, Visual Analogue Scale Received : 11. 04. 27 Revised : 11. 05. 25 Accepted : 11. 05. 26

I

. 緖論

80 80-90

80 6

ABSTRACT

Objectives :This study was carried out to compare the Sweet Bee Venom (referred to as Sweet BV hereafter) acupuncture parallel treatment to treatment with acupuncture only for the patient diagnosed with lumbar spine sprain and find a better treatment.

Methods :The subjects were patients diagnosed with lumbar spine sprain and hospitalized at Suncheon oriental medical hospital, which was randomly divided into sweet BV parallel treatment group and acupuncture-only group, and other treatment conditions were maintained the same. Then, VAS (Visual Analogue Scale) was used to compare the difference in the treatment period between the two groups from VAS 10 to VAS 0, from VAS 10 to VAS 5, and from VAS 5 to VAS 0.

Result & Conclusion :Sweet BV parallel treatment group and acupuncture-only treatment group were compared regarding the respective treatment period, and as the result, the treatment period from VAS 10 to VAS 5 was significantly reduced in sweet BV parallel treatment group compared to the acupuncture-only treatment group, but the treatment period from VAS 5 to VAS 0 did not show a sig- nificant difference. Therefore, it can be said that sweet BV parallel treatment is effective in shortening the treatment period and controlling early pain compared to acupuncture-only treatment.

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Sweet Bee Venom Sweet BV

40-50 2840 melittin

gel filtration

Anaphylactic shock

2010 11 12 2011 1 31

Sweet BV

II

. 연구대상 및 방법

1 2010 11 12 2011 1 31

50 36 14

1 3

Sweet BV skin test

4 3

7 CT MRI

Sweet BV

F/U loss

2

.

1 Sweet BV

Sweet BV Gel filtration chromatography pr- opionic acid / urea polyacrylamide gel electrophor-

esis 10,000

Sweet Bee Venom

0.1 PH

1cc Sweet BV

0.1cc 1 1

2 0.30 40

1 2 20

3

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Hot pack, TENS, ICT 1 1 5-15

4 Table 1

5 1 1 5

3 VAS : Visual Analogue Scale 10

0

4 SPSS 18.0 for windows

19, 17 Levene

0.05 Table 2

Table 3 t-

t-

III

. 結果

1.

1 36 17 19

42.75 13.896

Sweet BV 11 8

44.37 12.07

6 11

40.94 15.872

Table 4

2

1 VAS 10 VAS 0

Sweet BV 11.26 2.642

14.71 2365 p 0.001

Table 5

2 VAS 10 VAS 5 Sweet BV

5.95 1.615 9.29

1.993 Sweet BV p 0.001

Table 6 VAS 5 VAS 0

Sweet BV 6.32 1.668

6.41 1.417

p 0.05 Table 7

IV

. 考察

80 2-3

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10 Sweet BV

40-50 2840

melittin gel filtration

anaphylactic shock

2010 11 12 2011 1 31

36 Sweet BV

Sweet BV 19 17

VAS VAS 10 VAS 0

Sweet BV

11.26 2.642 14.71

2365 Sweet BV

VAS 10 VAS 5 Sweet BV

5.95 1.615 9.29

1.993 Sweet BV

VAS 5 VAS 0 Sweet

BV 6.32 1.668

6.41 1.417

3 Sweet BV

Sweet BV

VAS

V

. 結論

2010 11 12 2011 1 31

36 Sweet BV

VAS

1. Sweet BV Sweet BV p 0.001

2. Sweet BV

VAS VAS 10 VAS 5

Sweet BV p 0.001

3. Sweet BV

VAS VAS 5 VAS 0

Sweet BV

p,0.05

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Sweet BV

VI

. 參考文獻

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2002 : 396

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Clinical Analysis of Low Back pain. Korean J Fam Med 1991 Mar; 12(03): 17~22

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Effect of Chuna Treatment(Manupulation) on Lumbar Sprain Caused by Traffic Accident.

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2000 : 762-3

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Herbal name Scientific name Drug name Dose(g)

Angelica sinensis D^IELS. Radix Angelicae Sinens 12

Chaenomeles sinensis K^DEHNE. Fructus Chaenomelis 8

Achyranthes bidentata B^L. Radix Achyranthis Bidentatae 8

Glycyrrhiza uralensis F^ISCH. Radix Glycyrrhizae 7

Corydalis turtschaninovii B^ESS. Rhizoma Corydalis 7

Cyperus rotundus L. Rhizoma Cyperi 6

Cinnamomum cassia P^RESL. Ramulus Cinnamomi 4

Prunus persica B^ATSCH. Semen Persicae 4

Paeonia suffruticosa A^NDR. Cortex Moutan Radicis 4

Pinellia ternata B^REIT. Rhizoma Pinelliae 4

Amomum kravanh P^IRREex G^AGNEP. Fructus Amomi Rotundus 4

Paeonia lactiflora P^ALL. Radix Paeoniae Alba 4

Atractylodes macrocephala K^OIDZ. Rhizoma Atractylodis Macrocephalae 4

ehmannia glutinosa L^IBOSCH. Radix Rehmanniae Recens 4

Caesalpinia sappan L. Lignum Sappan 4

Bupleurum chinense DC. Radix Bupleuri 4

Lindera strychnifolia V^ILLAR. Radix Linderae 4

Paeonia lactiflora P^ALL. Radix Paeoniae Rubra 4

Citrus unshiu M^ARCOR. Pericarpium Citri Reticulatae 4

Carthamus tinctorius L. Flos Carthami 4

Magnolia officinalis R^EHD. Cortex Magnoliae Officinalis 4

Table 1. Prescription of Dangguesu-san.

F p-value

VAS 10 to VAS 0 0. 615 0. 438

VAS 10 to VAS 5 0. 318 0. 577

VAS 5 to VAS 0 0. 589 0. 448

Table 2. Leven's Test for Equality of Variances

Group W df p-value

VAS 10 to VAS 0 Sweet BV acupuncture group 0.925 19 0.143

Acupuncture group 0.929 17 0.206

Table 3. Shapiro Wilk's test

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Sweet BV acupuncture group Acupuncture group

Sex(Male/Female) 11/8 6/11

Age 44.37 12.07 40.94 15.872

Table 4. General Characteristics in patient

N Mean Standard Deviation T

Sweet BV acupuncture group 19 11.26 2.642

-4.099***

Acupuncture group 17 14.71 2.365

Table 5. Duration of Treatment (VAS 10 VAS 0)

(*** p 0.001 , ** p 0.01, * p 0.05)

-5.561 ***

Table 6. Comparison of VAS between Sweet BV acupuncture group and Acupuncture group. (VAS 10 VAS 5)

(*** p 0.001 , ** p 0.01, * p 0.05)

-0.185

Table 7. Comparison of VAS between Sweet BV acupuncture group and Acupuncture group. (VAS 5 VAS 0)

(*** p 0.001 , ** p 0.01, * p 0.05)