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INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis

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Figure  1:  Ino80  haploinsufficiency  inhibits  intestinal  tumorigenesis  in  Apc min/+   mice
Figure 2: Ino80 haploinsufficiency increases apoptosis in intestinal tumor cells in Apc min/+  mice
Figure 3: Ino80 knockdown increases apoptosis in human colon cancer cells.  (A) Immunoblot analysis of Ino80 expression in  HT29 cells following a 72-h transfection with control or Ino80-specific siRNAs
Figure 4: Ino80 knockdown decreases replication rates and increases stalled replication forks in human colon cancer  cells
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