7'(! 1 ~ 2001
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Spontaneous Regression of Liver Metastasis in Stage
N-S
Neuroblastoma after Adrenalectomy - Case Report -Hak Jun Seo, M.D., Jae Hee Jung, M.D., Young Tack Song, M.D.
Department of Surgery, St, Mary's Hospital, The Catholic University of Korea Seoul, Korea
Prenatally diagnosed neuroblastomas have been reported in increasing numbers over the past several years. The vast majority are in favorable stages of the disease (stage I ,II ,N-S).
The authors experienced one case of stage N-S neuroblastoma of the adrenal gland with liver metastasis, which regressed spontaneously after removal by adrenalectomy. This patient was noticed to have an abdominal mass at prenatal ultrasonography performed at 36weeks of gestation. This tumor was a neuroblastoma of the left adrenal gland with multiple liver metastases. Left adrenalectomy and liver biopsy were performed at 3 months of age.
Thirty-eight months after surgery, an MRI demonstrated that the hepatic metastatic lesions had completely regressed without chemotherapy or radiation. (J Kor Assoc Pecliatr Surg 7(1):68-72, 2(01)
Index Words: Neuroblastoma, Prenatal diagnosis, Stage IV-S, Spontaneous regression
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Fig. 3. Microscopic findings (H & E, x 100). The tumor celis (T) are separated by fibrous septum from normal hepatocytes (N). Tumor is composed of small round celis, hyperchromatic and rosette formation.
Fig. 4. MRI of the abdomen 38months after operation, showing complete disappearance of the previous lesions (T2 weighted image).
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