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Population pharmacokinetic Analysis of Doripenem after Intravenous Infusion in Korean Patients with Acute Infections

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TABLE 2 Population PK parameter estimates of final model for doripenem a
FIG 2 Goodness-of-fit plots: (A) conditional weighted residuals (CWRES) versus time; (B) conditional weighted residuals (CWRES) versus population model-predicted concentration (PRED); (C) observed concentration versus population model-predicted concentratio
FIG 3 Visual predictive check for 250-mg (left) and 500-mg (right) dosing groups by the use of simulated concentrations and 1,000 virtual data sets
FIG 5 Probabilities of target attainment (fT MIC above 40%) with various dosing regimens (a dosing interval of 8 or 12 h, an infusion time of 1 or 4 h, and a dose of 125, 250, or 500 mg) for simulated 60-kg patients infected with

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