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A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type-Inducible Gene Overexpression

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Academic year: 2021

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Fig. 1. Plasmid construction. Plasmid construction of neuronal cell type–inducible (NSE::Luci) or general (SV::Luci) luciferase overexpression vector
Fig. 2. Luciferase expression pattern of neural stem cells introduced with a neuronal cell type–inducible luciferase overexpression system (NSE::Luci-NSCs) in  normoxia and hypoxia
Fig. 4. Neuronal differentiation potency. Neuronal differentiation potency of NSCs was confirmed by fluorescence staining specific for each neuron
Fig. 5. High luciferase expression pattern after differentiation into neurons. (A) The luciferase expression level in neural stem cells and differentiated neu- neu-rons was compared by luciferase assay
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