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Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis

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Figure 1.  Detection of cells that express Thy-1 or αSMA in tumor stroma. Images of representative human lung  adenocarcinomas with low levels (case 4) or high levels (case 11) of Thy-1 and αSMA
Figure 3.  Thy-1-expressing cells localize within the tumor interstitium and on the tumor periphery
Figure 4.  Stromal cells that co-express Thy-1 and αSMA. Merged fluorescence micrographs of human lung  adenocarcinoma tissue sections co-stained with antibodies that detect Thy-1 or αSMA (pseudocolored green  and red, respectively)
Figure 6.  Gene Ontology term enrichment in the CAF proteomic signature. The 10 most highly enriched terms  among peptides up-regulated in CAFs (top pie chart) or down-regulated in CAFs (bottom pie chart) relative to  LFs
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