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Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses

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Academic year: 2021

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Table 1: p38 family members and their functions in inflammatory responses. p38 isoform
Figure 1: p38-regulated signaling pathways in inflammatory responses. Inflammation-derived cytokines such as TNF-
Figure 2: Chemical structures of representative novel p38 inhibitors. Promising therapeutic activities of these inhibitors against inflammatory diseases such as RA encourage the continuous progression for clinical trials.
Table 3: Naturally occurring compounds that inhibit p38 signaling in macrophages.

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