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Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome

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Academic year: 2021

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FIGURE 1. Specific activation of the pyrin inflammasome by ribotoxic
FIGURE 2. p38 MAPK-dependent activation of caspase-1. A and C, immu- immu-noblots of caspase-1 in lysates of 293T-C1AP cells stimulated with anisomycin (Aniso) for 5 h in the absence (untreated (Un)) or presence of SB203580 (SB) or SP600125 (SP) (A) or wit
FIGURE 4. Role of ASC and microtubules in anisomycin-induced caspase-1
FIGURE 5. Anisomycin does not activate caspase-1 in mouse peritoneal

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