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Prediction method of condition-specific protein-protein interactions using gene expression profiles

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Fig.  1.  Methods  Overview.  조건  특이적인  PPIs  예측방법을  비교하기  위하여  기존 에  알려진  PPI  데이터베이스를  통합하고  (A)  논문  큐레이션을  통해서  줄기세포  및  종양세포에서  특이적인  PPIs를  구축하였다
Fig. 2. DNA Microarray experiment and gene expression profiles data. (A)  마이크로어 레이  위에  알려진  유전자의  탐지자를  고정하고  샘플로부터  RNA를  추출한  후  형 광처리하여  마이크로어레이에  혼합하는  과정
Fig. 3. Procedure for quantile normalization method
Fig. 4. Protein-protein interactions in cellular signalling pathway.  배아줄기세포의  만 능성과  분화에  관련된  신호전달경로는  다양한  단백질  간  상호작용으로  구성된다  (그림출처: CST, Inc)
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